Bio-hazard Battle, titled Crying in Japan, is a 1992 2D side-scrolling shoot 'em up sharing similar gameplay to the cult-classic Zero Wing, also released for the Mega Drive/Genesis. Following suit with other shoot 'em ups, it followed the loosest of plots. Generally set in dilapidated and run down cities or infested jungles, one could only infer from the title, enemies and scenery that the player was supposed to be battling some sort of mutant, alien or bio-weapon outcome. Even this barely holds up, because the four "ships" that the player could choose looked just like the rest of the enemies, very organic and seeming to be crosses of several Earth-like creatures.