Pac-Man vs. is a multiplayer game for the GameCube which utilizes the GC-GBA connectivity.

One person uses the GBA screen to play pacman in the classic way whereas your friends are playing on the tv as ghosts in a 3D maze trying to get you. The aim is to get a set amount of points by collecting as many pellets as you can. When a ghost does get pacman, the person who caught pacman and the person playing pacman swap pads.

This is a fantastic game which is one of the best multiplayer games around.

(screenshots taken from nintendo.com)