Sanitarium is a point-and-click adventure game released in 1998 by ASC Games. A psychological thriller often praised for its atmosphere and originality, Sanitarium tells the story of a man stricken with amnesia, trying frantically to unveil the details of his institutionalization in a terrifying asylum. The search for his own identity takes place within the grounds of the sanitarium and in the main character's delusions and flashbacks, as he confronts the ghosts of his past. The dark mood and graphics of the game are matched by an equally ominous musical background.

The game uses a 3rd person perspective and a non-tiled 2D navigation system. Each world from each of the 9 chapters (over which the game spans) carries a distinct atmosphere that presents either the real and imaginary world of the main protagonist. In many cases, it is unclear to the player which of these worlds the game is currently in play. This indistinction underlines much of the psychological horror portrayed in the game.